Alysha Chua

Alysha Chua

Research Biochemist

Biotechnologies

Epiphanies across multi-disciplinary teams

My expertise spans biotechnology, biopharmaceutical analysis and cell culture. I lead the Callaghan Innovation Tissue Culture Laboratory where I design and implement cell-based assays for evaluating the safety and efficacy of novel materials, with a focus on food bioactives and nutraceuticals.

My career has included working on photosynthetic cyanobacteria and algae in London, studying plant stress tolerance in Ireland before coming to New Zealand. The combination of projects in fields like chemistry, metabolic modelling and agriculture taught me the importance of interdisciplinary approaches and having an integrated view of science. Exposure to a wider range of skills and perspectives has enabled me to make novel connections that researchers within a single discipline might miss. 

My aim is to provide customers with affordable and high-throughput cell-based assays. To achieve this, I am expanding our cell culture portfolio to include perfused 3D cultures using organs-on-a-chip with the goal of creating 3D cultures with the scale and reproducibility of 2D cultures.

Areas of expertise
  • Cell-based assays, with an emphasis on safety and efficacy testing
  • Biochemical assays
  • Microbiology
  • Molecular biology
Education
  • Doctor of Philosophy (PhD) in Plant Stress Tolerance, Waterford Institute of Technology, Ireland 2019 
  • Master of Research (MRes) in Systems & Synthetic Biology, Imperial College London, UK, 2014 
  • Bachelor of Science (BSc) in Biotechnology, Imperial College London, UK, 2013 
Selected publications
  • Chua, Alysha, Orla L. Sherwood, Laurence Fitzhenry, Carl K.-Y. Ng, Paul F. McCabe, and Cara T. Daly. ‘Cyanobacteria-Derived Proline Increases Stress Tolerance in Arabidopsis Thaliana Root Hairs by Suppressing Programmed Cell Death’. Frontiers in Plant Science 11 (14 December 2020): 490075. https://doi.org/10.3389/fpls.2020.490075.
  • Chua, Alysha, Laurence Fitzhenry, and Cara T. Daly. ‘Sorting the Wheat From the Chaff: Programmed Cell Death as a Marker of Stress Tolerance in Agriculturally Important Cereals’. Frontiers in Plant Science 10 (26 November 2019): 1539. https://doi.org/10.3389/fpls.2019.01539.
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